In what way are you having issues with Office 2016 and Designer ES4?
It should be mentioned that product support for LiveCycle Designer ES4 is no longer available. AEM Forms Designer 6.4, which is generally available now is supported on Windows 10.
Here is the product support matrix for ES4 at [1]. Here is the product support matrix for AEM forms 6.4 at [2].
[1] Adobe LiveCycle ES4 supported platforms guide
[2] Adobe Experience Manager Help | Supported Platforms for AEM Forms on JEE