Hi Tracey,
Thanks for reaching out to the community.
Adobe campaign doesn't support email as inbound channel that being said you can use a monitored email address as your reply address in adobe campaign server and you can write some rule to parse the incoming rules for that mailbox and respond to customers according to that. Raise a support ticket to help you configure a supervised mail box as reply address, it's quite straight forward but you will be needing some inputs from the Deliverability team about the same.
Regards,
Amit