Hi Alex,
We are doing this as well-working on the configuration now. We make a Set Up/Maintenance project which will hold the issues which are then converted to "sub-projects". We will be using queue topics/groups to help organize since our creative material will need to be grouped by "message". My colleague found great text mode in the community last week for issue/converted project reporting, see attached.
Coincidentally, I posted a few months ago regarding pulling information from the Portfolio>Program>Project>Issue>Sub-project. Here is the link should you find it helpful
https://community.workfront.com/p/fo/st/topic=39&post=8260#p8260.
Also, a document posted here,
https://community.workfront.com/p/do/si/topic=82, for copying queue details was extremely helpful, although I am able to pull through data without having to copy the issue form as a project form (although that does work and I may use in the future).
You may already be doing the above but wanted to chime in should someone else be interested as well.
Look forward to hearing what others do, thank you for the post!