Hi,
Yes, you can change the "required" status of a field(s) using the validate.nullTest in either Formcalc or Javascript. You could use script like this in the exit event of the radio button:
if (this.rawValue == 1) then
DateTimeField1.validate.nullTest = "error"
else
DateTimeField1.validate.nullTest = "disabled"
endif
"error" sets the referenced field to required; whereas "disabled" changes it back to not required.
Good luck,
Niall