Thank you for your reply. It's for regulatory reasons in the EU region. You can read more about it by searching up GDPR. This idea of deleting the cookie occurred to us previously, but after full consideration it is not robust enough to be a desirable enterprise solution for us.  

HI @Amelia_Waliany , thank you for following up. I was not able to resolve the issue through here or Adobe support.  There appears to be no way to stop Adobe Target setting the mbox cookie as the script loads.

Thanks. To clarify I would like to disable first party cookie persistence in at.js.  How to do this?

Hello, We would like to disable both first and third party cookies set by Target, that is no cookies at all set by Target, for some of our site visitors.  Is there a way to set something in TargetGlobalSettings to stop all first and third party cookies being set? I know there is a setting for third ...