Getting the below exception while starting the instance
javax.jcr.LoginException: Can neither derive user name nor principal names for bundle com.day.cq.wcm.cq-wcm-core  and sub service design-cache-service
the instance does not start
please can you advise.
Looks like you removed a default setting from AEM (the service-user-mapping for this bundle). If that's a lower environment, I would suggest to rebuild it from scratch.
If you cannot afford that but need to fix it, you should check the OSGI configuration manager for the string "design-cache-service" and compare it with an instance where this error does not appear.