Can I pull open/click/unsubscribe/bounced metrics on 2 lists used for the same program?

If you create an email performance report and only select the emails within the program, then in the smart list, add a filter to only include the purchased leads list. Run the report and you'll see all the data for just that list. Switch the filter to the sales rep's accounts list and repeat the process.

Matt is absolutely correct. You can also just clone your list and change the filters so you can regularly track both without having to update your filters. Best of luck, Jeff

Thanks guys!
Is there a way I can create a report that shows purchased vs sales leads without having to pull the information manually?

What you can do is add a "Group by Segmentations" to the Setup of the report (this presumes that you will first set up a Segmentation to identify your two types of leads).

By doing this, the report will separate the two... but it comes with a catch: you won't see a breakdown by email anymore, only by the segmentation groupings. In other words, if your program has five emails, the report would normally show you each email and the stats for each. By adding this segmentation to it, it will combine the results for all of the emails as they relate to each individual segmentation.