From a pure tech point of view, tt can be achieved if you collect the time and day as part of the data collection.
e.g. if you are using Adobe Analytics server side forwarding then a plugin or client-side code can be used to populate time or day variables here
The use-case is important if you want to retarget users who have visited on a Monday then creating the Traits and Segments in Audience Manager using the above is appropriate. i.e. The users will qualify from the first Monday until the Trait expires.
However, if your use-case is to personalise a banner for users who visit the website on Mondays then the audience should be in Adobe Target (or other personalisation tool) so only qualify based on the current time.
Creating the audience in Analytics could work but bear in mind the latency factor.
