Try the following options:1. Delete the following folders: Win
XP:C:\Documents and Settings\\Application
Data\Adobe\Designer\8 C:\Documents and Settings\\Local
Settings\Temp\Adobe\Designer Win Vista:C:\Users\\AppData\Roaming\Adobe\Designer\8.0C:\Users\\AppData\Local\Temp\Adobe\DesignerThen re-run LC Designer ES2. 2.
Also make sure only one instance of Microsoft Visual C++ 2005
Redistributable is present in Add/Remove programs.Let me know if this
does the trick for you.