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Level 10

I talked to the QA team and this is what they suggested:

This sounds sort of familiar.

If Reader 10.0.0 is the default handler, then that is what Designer will use in the preview so it's most likely something between Reader and Designer.

A few things to try:

* Monitor active processes and see if Reader is floating about in memory before Designer starts or before they PDF Preview. It could be possible Reader is hanging around in a state that isn't expected and Designer trying to instantiate it in the PDF Preview is causing this to come up. Is Reader hanging around after Designer closes?

* Try setting Reader up to run outside of Designer (Edit->Preferences...->Internet -- uncheck "Display PDF in browser") and see if that works? This will force Reader/Acrobat to open on its own, bypassing the run-in-browser code.