I also got a warning about an empty page and a pdf that could not be Read Out Loud. I just discovered that en dashes (option-hyphen), ellipses (...) and apostrophes seem to break the Read Out Loud feature. If I change the en dash to a regular hyphen, the ellipsis to three periods, and the proper typographic apostrophe to a prime (i.e. turn off smart quotes), then Read Out Loud seems to work. What these three characters all have in common is that they all use the option key whey you type them (on a Mac). I hope there is a fix for this. I do not wish to compromise the "traditional" layout to accommodate the accessible version.