Geting Error while running IIS with Dispatcher

[Heena06]

Hi,

When I added New Site on IIS and browse it, I am getting below error msg. Please suggest what can be the reason.

Thanks,

Heena

[SundeepKatepally]

do send the back end logs.? 

Looks like as per the screenshot IIS is not correctly configured and pointed to origin (publish server.)