Not sure how to look into this. I have a couple html5 articles that get into the app, but once viewing them they are either way too small or positioned like -200px to the left edge of the ipad. These all work in every browser and in other apps that deliver html5 apps to mobile devices. I can't seem to find anything on this issue with DPS.
I used Dreamweaver CC to set up a responsive html page using the provided templates.
Then I built the article by hand.
Then I used Chrome and Safari to create/edit new classes within each media query until the article looked good on two phone sizes and one tablet size.
I then duplicated the entire folder and set up a second article. It was a similar yet different enough article that I had to make some tweaks to some of the classes. Each was zipped independently with their own CSS, images, and fonts.
Not exactly the same issue, but I've seen responsinve HTML articles look significantly different than in the desktop browsers (Chrome and Safari) that I used to edit the CSS and test multiple devices. Mostly size issues. I think I remember other folks having similar differences between what they see when prepping the HTML and what they see in the app. A quick search in the forums should list the threads where it was discussed.