We did eventually resolve the issue. Here is what was required from start to finish. For the time zone error it was step 4 that fixed the problem.
1) Marketing server hosts, Install MYSQL Client on adobe campaign marketing servers. The new MYSQL client is required for a new adobe campaign connection.
2) Marketing server hosts, Create a link between libmysqlclient_r.so.18 and libmysqlclient.so.18 so that libmysqlclient_r.so.18 is recognized but redirects to libmysqlclient.so.18
3) Network, Enable network connection between adobe campaign instance and the MYSQL DB host
4) MYSQL DB, Populate DB time zone table ‘mysql.time_zone_name’ using script mysql_tzinfo_to_sql